V Papadopoulos Selected Research

25R)-20alpha-spirost-5-en-3beta-yl hexanoate (22R

1/2012	Caprospinol: discovery of a steroid drug candidate to treat Alzheimer's disease based on 22R-hydroxycholesterol structure and properties.
1/2010	Caprospinol reduces amyloid deposits and improves cognitive function in a rat model of Alzheimer's disease.

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V Papadopoulos Research Topics

Disease

9	Neoplasms (Cancer) 06/2013 - 09/2000
6	Alzheimer Disease (Alzheimer's Disease) 01/2012 - 01/2001
4	Neoplasm Metastasis (Metastasis) 10/2007 - 01/2003
3	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2021 - 06/2013
3	Inflammation (Inflammations) 05/2014 - 01/2006
3	Familial Mediterranean Fever (Periodic Disease) 01/2012 - 04/2004
3	Breast Neoplasms (Breast Cancer) 11/2004 - 09/2000
2	Prostatic Neoplasms (Prostate Cancer) 11/2015 - 01/2003
2	Anxiety Disorders (Anxiety Disorder) 01/2012 - 01/2012
2	Teratocarcinoma 06/2011 - 08/2007
2	Fever (Fevers) 05/2007 - 11/2004
1	Overweight 02/2016
1	Hyperplasia 11/2015
1	Menorrhagia 01/2015
1	Obesity 01/2015
1	Asthma (Bronchial Asthma) 01/2015
1	Body Weight (Weight, Body) 05/2014
1	Neuroinflammatory Diseases 01/2012
1	Cognitive Dysfunction 01/2012
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 01/2012
1	Peripheral Nerve Injuries 01/2012
1	Behcet Syndrome (Behcet's Syndrome) 01/2012
1	Necrosis 01/2012
1	Oligohydramnios 01/2011
1	Pre-Eclampsia (Preeclampsia) 01/2011
1	Fissure in Ano (Anal Fissure) 11/2010
1	Pain (Aches) 11/2010
1	Gliosis 01/2010
1	Amyloid Plaque 01/2010
1	Pheochromocytoma 08/2007
1	Serositis 05/2007
1	Glioma (Gliomas) 01/2006
1	Nervous System Diseases (Neurological Disorders) 01/2006
1	Mood Disorders (Mood Disorder) 01/2006
1	Brain Injuries (Brain Injury) 01/2006
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2006
1	Carcinoma (Carcinomatosis) 02/2005
1	Transverse Myelitis (Necrotizing Myelitis) 01/2005
1	Colorectal Neoplasms (Colorectal Cancer) 11/2004
1	Ductal Carcinoma 11/2004

Drug/Important Bio-Agent (IBA)

7	SteroidsIBA 06/2013 - 01/2001
5	Pharmaceutical PreparationsIBA 06/2013 - 09/2000
5	LigandsIBA 06/2013 - 01/2001
5	GABA-A Receptors (GABA(A) Receptor)IBA 01/2012 - 09/2000
3	CholesterolIBA 01/2012 - 01/2001
3	Proteins (Proteins, Gene)FDA Link 01/2012 - 01/2010
3	22-hydroxycholesterolIBA 01/2012 - 01/2006
2	Testosterone (Sustanon)FDA Link 01/2021 - 08/2015
2	Diethylhexyl Phthalate (DEHP)IBA 01/2015 - 05/2014
2	25R)-20alpha-spirost-5-en-3beta-yl hexanoate (22RIBA 01/2012 - 01/2010
2	PyrinIBA 01/2012 - 05/2007
2	PregnenoloneIBA 01/2012 - 08/2007
2	Amyloid beta-PeptidesIBA 08/2007 - 01/2001
2	NeurosteroidsIBA 01/2006 - 01/2003
2	Ginkgo biloba extract (Rokan)IBA 01/2001 - 09/2000
1	AndrogensIBA 11/2015
1	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 11/2015
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 11/2015
1	phthalic acid (phthalate)IBA 05/2014
1	Endocrine DisruptorsIBA 05/2014
1	Anti-Anxiety Agents (Anxiolytics)IBA 01/2012
1	CytokinesIBA 01/2012
1	etifoxineIBA 01/2012
1	N- benzyl- N- ethyl- 2- (7,8- dihydro- 7- methyl- 8- oxo- 2- phenyl- 9H- purin- 9- yl)acetamideIBA 01/2012
1	BenzodiazepinesIBA 01/2012
1	Hypnotics and Sedatives (Sedatives)IBA 01/2012
1	Antidepressive Agents (Antidepressants)IBA 01/2012
1	solasodineIBA 06/2011
1	EnzymesIBA 01/2011
1	Nitroglycerin (Dynamite)FDA LinkGeneric 11/2010
1	Lactulose (Duphalac)FDA LinkGeneric 11/2010
1	Lidocaine (Xylocaine)FDA LinkGeneric 11/2010
1	Ointments (Pastes)IBA 11/2010
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2010
1	PK 11195 (PK11195)IBA 01/2010
1	NucleotidesIBA 01/2010
1	isoquinolineIBA 01/2010
1	Diazepam (Valium)FDA LinkGeneric 01/2010
1	cholesterol-binding proteinIBA 01/2010
1	4'-chlorodiazepamIBA 01/2010
1	tau Proteins (tau Protein)IBA 01/2010
1	Pregnanolone (Allopregnanolone)IBA 01/2006
1	AcidsIBA 02/2005
1	Methylprednisolone FDA LinkGeneric 01/2005
1	AlbuminsIBA 11/2004
1	CreatinineIBA 11/2004
1	Alkaline PhosphataseIBA 11/2004
1	BilirubinIBA 11/2004

Therapy/Procedure

3	Therapeutics 11/2015 - 01/2003
2	Aftercare (After-Treatment) 06/2011 - 11/2010
2	Drug Therapy (Chemotherapy) 10/2007 - 11/2004
1	Cesarean Section (Caesarean Section) 02/2016
1	Endometrial Ablation Techniques 01/2015
1	Curettage 01/2015
1	Sphincterotomy 11/2010
1	Lateral Internal Sphincterotomy 11/2010
1	Neoadjuvant Therapy 10/2007
1	Hepatectomy 10/2007
1	Radiotherapy 11/2004
1	Radiofrequency Ablation 11/2004